Never stop Zoloft or Lexapro suddenly. Both medications need a gradual taper — usually over several weeks — guided by your doctor. Stopping cold turkey triggers SSRI discontinuation syndrome: brain zaps, dizziness, nausea, and mood crashes. These symptoms aren't dangerous, but they're very uncomfortable. The good news? They're almost entirely preventable with the right tapering plan. If you've been on Zoloft, Lexapro, etc. for a while and you're thinking about stopping, you'v